Description The ViPrimePLUS Feline Coronavirus RT-qPCR Kit is a Taqman probe-based real-time PCR assay for the detection of Feline Coronavirus genome in faeces and saliva. Feline Coronavirus (FCoV) is a single stranded RNA virus which infects wild and domestic cats. The virus is often classified into two groups. The highly pathogenic strain, feline infectious peritonitis viruses (FIPV) may cause lethal systemic disease, while the less severe enteric coronaviruses (FECV) infection is mainly asymptomatic or only causes mild diarrhoea which is self-limiting. The “in vivo mutation” theory suggested that FIPV arises from the mutation of the parental FECV in the gastrointestinal tract of an infected cat and spreads systemically, causing FIP. FCoV is shed in faeces and in lesser amount in the saliva, thus they are spread primarily via faecal-oral route. Cats with weak immune system tend to develop the effusive or ‘wet’ form of the disease, where the accumulation of fluids in the abdomen and chest leads to breathing difficulty. For cats with partial mediated immune system may develop the non-effusive or ‘dry’ form of the disease in which granuloma lesions are observed in eyes, central nervous system and peritoneal cavity, resulting in more diverse signs. ViPrimePLUS Feline Coronavirus RT-qPCR Kit is intended for research use only.
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ViPrimePLUS Feline Coronavirus RT-qPCR Kit
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