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TFA-Amino modifier CPG 500

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产品名称: TFA-Amino modifier CPG 500
产品型号: 11860 21860 31860 41860 51860
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简单介绍

TFA-Amino modifier CPG 500 11860 21860 31860 41860 51860


TFA-Amino modifier CPG 500  的详细介绍

TFA-Amino modifier CPG 500

Oligonucleotide synthesis
Cat. # Quantity Price Lead time
11860 100 mg  60.00$ in stock
 
21860 250 mg  120.00$ in stock
 
31860 500 mg  230.00$ in stock
 
41860 1 g  380.00$ in stock
 
51860 5 g  1450.00$ 21 days
 
Bulk inquiry 

This high load, 500 ? controlled pore glass solid support is designed for the synthesis of oligonucleotides containing up to 50 bases with a 3'-amino group. Amino group is protected with trifluoroacetyl (TFA) protection which is easily removed under standard deblock conditions.

The reagent is based on hydroxyprolinol core - a universal non-nucleoside structure that is naturally 100% chiral (no isomers formed upon condensation), and stable to all conditions of oligonucleotide synthesis and deblock.

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General properties

Appearance: off-white beads
Quality control: NMR 1H and HPLC-MS (95%) of bound reagent, loading measurement
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download

Oligo synthesis details

Pore size, ?: 500
Typical loading, umol/g: 70?90
Coupling conditions: standard coupling, identical to normal nucleobases
Cleavage conditions: ammonia, 2 h at room temperature
Deprotection conditions: identical to protected nucleobases

Product citations

  1. Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
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