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Pentynoic acid STP ester

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产品名称: Pentynoic acid STP ester
产品型号: 30720 40720 50720 60720
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简单介绍

Pentynoic acid STP ester 30720 40720 50720 60720


Pentynoic acid STP ester  的详细介绍

Pentynoic acid STP ester

Cat. # Quantity Price Lead time
30720 10 mg  110.00$ in stock
 
40720 25 mg  210.00$ 5 days
 
50720 50 mg  410.00$ in stock
 
60720 100 mg  695.00$ in stock
 
Bulk inquiry 

This water soluble alkyne activated ester reagent is used for the attachment of alkyne group to variois biomolecules such as proteins, and peptides. Amino-DNA, and other amines can be used as well. Since natural proteins do not contain alkynes, but almost always contain amines (lysines), this molecule is an "adaptor" to turn natural amines into alkynes.

Use this product to enable any of your proteins for Click Chemistry.

This is an STP (sulfotetrafluorophenyl) ester. STP esters are similar to NHS esters, but possess higher hydrophilicity, and water solubility. It works fine in pure aqueous reactions without addition of organic co-solvent, and is best suited for the modification of proteins.

Sulfotetrafluorophenyl ester of pentynoic acid
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Recommended protocol

NHS ester labeling of amino biomolecules

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General properties

Appearance: colorless solid
Mass spec M+ increment: 80.0
Molecular weight: 348.20
Molecular formula: C11H5F4NaO5S
Solubility: good in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download

Product citations

  1. Samuelsen, S.V.; Maity, A.; Nybo, M.; Macaubas, C.; L?nstrup, L.; Balboni, I.M.; Mellins, E.D.; Astakhova, K. Novel Phospholipid-Protein Conjugates Allow Improved Detection of Antibodies in Patients with Autoimmune Diseases. PLoS One, 2016, 11(6), e0156125. doi: 10.1371/journal.pone.0156125
  2. Maity, A.; Macaubas, C.; Mellins, E.; Astakhova, K. Synthesis of Phospholipid-Protein Conjugates as New Antigens for Autoimmune Antibodies. Molecules, 2015, 20(6), 10253–10263. doi: 10.3390/molecules200610253
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