Alt. Names
HA6116; HD4; HDAC-A; HDAC4; HDACA; Histone deacetylase 4; histone deacetylase A; KIAA0288
Specificity:
Phospho-HDAC4 (Ser632) Antibody detects endogenous levels of HDAC4 only when phosphorylated at Serine 632
Immunogen:
A synthesized peptide derived from human HDAC4 around the phosphorylation site of Serine 632
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Histone deacetylase 4 (HDAC4) is a histone deacetylase that represses transcription when tethered to a promoter. It has been shown to interact with MEF2C, Zinc finger, CBX5, Nuclear receptorco-repressor1 and HDAC3 (1, 2, 3, 4, 5). In neurological findings, HDAC4 has been shown to shuttle between the nucleus and cytoplasm, controlling a transcriptional program essential for synaptic plasticity and memory. The nuclear import of HDAC4 represses genes encoding constituents of central synapses, thereby affecting synaptic architecture and strength (6).
Please refer PDF file for Western, Immunofluorescence analysis, Chromatin immunoprecipitation analysis or other QC data.
Product is for research use only. Not for human use.
本公司网站所展示销售的产品仅供科研!
沪公网安备 31011202007337号