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H3K79me2MouseMonoclonalAntibody

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产品名称: H3K79me2MouseMonoclonalAntibody
产品型号: A90002-5
产品展商: 其它品牌
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发布时间:2020-06-01

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H3K79me2MouseMonoclonalAntibody


H3K79me2MouseMonoclonalAntibody  的详细介绍
Product Information

H3K79me2 Mouse Monoclonal Antibody

Clonality: Mouse IG1 Source: Mouse  
Applications: WB: 1:500-1:2000 Cross-Reactivity: HMRat;  
Concentration: 100 ug/100 ul  Detected band (by western)MW: 15 kD  
   

Alt. Names

H3 histone antibody, HIST1H3A antibody, Histone cluster 1, H3a antibody

Specificity:

The Histone H3 (di methyl K79) mouse monoclonal antibody can recognize endogenous Histone H3 (di methyl K79) proteins.

Immunogen:

Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH.

Storage Condition and Buffer:

Store at -20°C. Stable for one year from the date of shipment. 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol

Background:

H3K79 methylation is one of the gene activation markers.  DOT1L methyltransferase usually involves in H3K79 methylation, playing essential roles in embryonic development, hematopoiesis, cardiac function and the development of leukemia.

To detect marker H3K79 methylation status, pick from our H3K79 polyclonal antibody series or H3K79 mouse monoclonal antibody series.

PDF:

SDS:

References:

1. Robert A Copeland. Protein methyltransferases in cancer. (2013) AACR Annual Meeting.

2. Roy M Pollock. Preclinical Characterization of a Potent, Selective Inhibitor of the Protein Methyltransferase DOT1L for Use in the Treatment of MLL-Rearranged Leukemia. (2012) 54th ASH Annual Meeting and Exposition. 

Product is for research use only. Not for human use. 

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