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补体C4

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产品名称: 补体C4
产品型号: A402
产品展商: Quidel
美元($)价格: 286.00 元
欧元(€)价格: 0.00 元
人民币(¥)价格: 0.00 元
产品文档: 无相关文档
发布时间:2020-08-02

简单介绍

补体C4


补体C4  的详细介绍

For Research Use Only. Not for use in diagnostic procedures.

Purified human complement component C4. C4 is one of the proteins unique to the Classical Complement Pathway. The 200 kD C4 protein is made up of three peptide chains linked by disulfide bonds and contains a thioesterbond. When the classical pathway is activated, C1s cleaves C4 to C4a (a weak anaphylatoxin) and C4b. C4b can then bind covalently to a target surface or complex. It can then function as an opsonin or participate as part classical pathway convertase. C4 has been shown to exist as two separate "complotypes" C4A and C4B. These have been shown to have different biological properties.

All Quidel complement components are tested for functional activity in a standard lytic or applicable functional ***** and for biochemical purity by SDS-polyacrylamide gel electrophoresis. Please refer to the Certificate of Analysis for lot specific information on functional titer.

Quidel's purified human complement components are useful in a wide variety of immunochemical and research applications. For assistance with a specific protocol, please contact Quidel Technical Support.

References

Schifferli JA, Paccaud J. Two Isotypes of human C4, C4A and C4B, have different structure and function, Complement and Inflammation 6:19-26, 1989.

Nicholson-Weller, Butko, P, Wessels, M. Role of Complement Component C1q in IgG Independent Opsonophagocytosis of Group B Streptococcus, J. Immunol 163:2761-2768, 1999.

Features & Benefits

Feature Benefit

Product Specifications

Product Spec Name Product Spec Data
Concentration

1.0 mg/mL

Volume/vial

250 μL/vial

Storage

At or below –70°C

Purity

> 90%

Buffer

PBS

Ordering Information

Catalog Number Kit Size / Case Size
A402
250 μL/vial

Product Documentation

PDF icon SDS

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