For Research Use Only. Not for use in diagnostic procedures.
A murine monoclonal antibody to human Factor H.
Specificity
This monoclonal antibody was raised against purified human Factor H. Studies have shown that this antibody functionally inhibits Factor H.
Quidel's Factor H monoclonal antibody has been used in a variety of experimental techniques including EIA and Western Blot. Please contact Quidel Technical Support for details on any applications.
References
Pangburn, M.K. Differences between the s of the complement regulatory proteins DAF, CR1 and Factor H on C3 Convertases, J Immunol 136:6, 1986.
Kraiczy P, Würrzner, R. Complement escape of human pathogenic bacteria by acquisition of complement regulators, Mol Immunol 43:31-44, 2006.
Atkinson, J.P., et al. Complement factor H and the hemolytic uremic syndrome, JEM 204:6, 1245-1248, 2007.
Sivaprasad, S. and Chong, N.V. The Complement system and age related macular degeneration, Eye 1-6, 2006.
Jokiranta, T.S., et al. Analysis of the recognition mechanism of the alternative pathway of complement by monoclonal anti-factor H antibodies: evidence for multiple interactions between H and surface bound C3b, FEBS Ltr 393(2-3):297-302, 1996.
Junnikkala, S. et al. Exceptional resistance of Human H2 Glioblastoma Cells to Complement Mediated Killing by Expression and Utilization of Factor H and Factor H Like Protein I, J Immunol 164, 2000.
Cheng Z., et al. Complement Factor H as a Marker for Detection of Bladder Cancer, Clin Chem 51:5, 2005.
