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补体C5

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产品名称: 补体C5
产品型号: A403
产品展商: Quidel
产品文档: 无相关文档

简单介绍

补体C5


补体C5  的详细介绍

For Research Use Only. Not for use in diagnostic procedures.

Purified human complement component C5. Complement component C5 is unique to the terminal complement pathway. 190 kD C5 protein is comprised of two chains (α 115 kD; ? 75 kD) and is present in plasma at 70 mg/L. Activation of either complement pathway can generate a C5 convertase enzyme capable of cleaving C5 to C5a (a potent anaphylatoxin) and C5b. Together with the other proteins of the terminal pathway, C5b forms the membrane attack complex or MAC.

All Quidel complement components are tested for functional activity in a standard lytic or applicable functional assay and for biochemical purity by SDS-polyacrylamide gel electrophoresis. Please refer to the Certificate of Analysis for lot specific information on functional titer.

Quidel's purified human complement components are useful in a wide variety of immunochemical and research applications. For assistance with a specific protocol, please contact Quidel Technical Support.

References

Nicholson-Weller, Butko, P, Wessels, M. Role of Complement Component C1q in IgG Independent Opsonophagocytosis of Group B Streptococcus, J. Immunol 163:2761-2768, 1999.

Barbashov, S., Wang C. Nicholson-Weller, A. Serum amyloid P component forms a stable complex with human C5b-6, J. Immunol. 158:3830-3835, 1997.

Koski, C., Dashell, S. Sublytic terminal complement complex decreases Po gene expression in schwan cells, J Neurochem 73(6):2321-2330, 1999.


Features & Benefits

Feature Benefit

Product Specifications

Product Spec Name Product Spec Data
Concentration

1.0 mg/mL

Volume/vial

250 μL/vial

Storage

At or below –70°C

Purity

> 90%

Buffer

PBS

Ordering Information

Catalog Number Kit Size / Case Size
A403
250 μL/vial

Product Documentation

PDF icon SDS

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