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Cy3-Crotamine Fluorescent tumor-cell specific agent

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产品名称: Cy3-Crotamine Fluorescent tumor-cell specific agent
产品型号: CRO002
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简单介绍

Cy3-Crotamine Fluorescent tumor-cell specific agent Crotamine is a basic peptide present in the venom of the South American rattlesnake Crotalus durissus terrificus. Multiple biological functions have been attributed to Crotamine. It is a natural cell-penetrating peptide with selective biological action towards actively proliferating cell types such as tumor cells. Moreover, it has been reported


Cy3-Crotamine Fluorescent tumor-cell specific agent  的详细介绍
Cy3-Crotamine Fluorescent tumor-cell specific agent Crotamine is a basic peptide present in the venom of the South American rattlesnake Crotalus durissus terrificus. Multiple biological functions have been attributed to Crotamine. It is a natural cell-penetrating peptide with selective biological action towards actively proliferating cell types such as tumor cells. Moreover, it has been reported that crotamine is a blocker of Kv1.3 (IC50 around 300 nM) as well as Kv1.1 and Kv1.2. It has analgesic properties and myonecrotic effects. In addition, crotamine belongs to the beta-defensin peptides and as such demonstrates antibacterial properties by interacting with lipid membranes. Cy3-crotamine is a fluorescent version of Crotamine.
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