产品资料

Phrixotoxin-2 Phrixotoxin-2, a blocker of Kv4.2 and Kv4.3 channels

如果您对该产品感兴趣的话,可以
产品名称: Phrixotoxin-2 Phrixotoxin-2, a blocker of Kv4.2 and Kv4.3 channels
产品型号:
产品展商: 其他品牌
产品文档: 无相关文档

简单介绍

Phrixotoxin-2 Phrixotoxin-2, a blocker of Kv4.2 and Kv4.3 channels Phrixotoxin-2 (PaTx2) has been isolated originally from the venom of the Chile fire tarantula Phrixotrichus auratus. Phrixotoxin-2 is a 31 amino acid peptide that contains three disulfide bridges. Phrixotoxin-2 specifically blocks recombinant Kv4.2 and Kv4.3 currents with IC50 values of 34 nM and 71 nM, respectively. It does so by


Phrixotoxin-2 Phrixotoxin-2, a blocker of Kv4.2 and Kv4.3 channels  的详细介绍
Phrixotoxin-2 Phrixotoxin-2, a blocker of Kv4.2 and Kv4.3 channels Phrixotoxin-2 (PaTx2) has been isolated originally from the venom of the Chile fire tarantula Phrixotrichus auratus. Phrixotoxin-2 is a 31 amino acid peptide that contains three disulfide bridges. Phrixotoxin-2 specifically blocks recombinant Kv4.2 and Kv4.3 currents with IC50 values of 34 nM and 71 nM, respectively. It does so by altering the gating properties of the channels. The inhibition of Kv4.2 and Kv4.3 currents is fully reversible upon washout. Kv4.1 is only slightly sensitive to Phrixotoxin-2 (maximal block of 20 by 300 nM). Kv1, Kv2 and Kv3 channel subfamilies are insensitive to this toxin.
产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!
相关产品
Morphiceptin Agonist of µ-opoid receptor 11CAS001-01000
Melittin Highly pure synthetic Melittin MEL01
Lys-conopressin-G Vasopressin-like peptide 11CON014-00500
Cy3-Crotamine Fluorescent tumor-cell specific agent CRO002
Crotamine Cell-penetrating peptide and ion channels blocker CRO001
Conantokin-G Selective inhibitor of NR2B-containing NMDAR 08CON009-00500
Purotoxin-1 Selective inhibitor of P2X3 receptors 011PUR001-00100
Obtustatin Inhibitor of the binding of α1β1 integrin to collagen IV 10OBT001-00100
Echistatin α1 isoform ECH001
ρ-Da1a – AdTx1 Selective antagonist of the alpha(1A)-adrenoceptor ADT001-00010
Rho-Conotoxin-TIA Blocker of α1-adrenoreceptor CON022-00100
MT7 – Muscarinic Toxin 7 Blocker of M1-subtype of muscarinic receptor MTX007-00100
NMB-1 NMB001-00100
GsMTx4 Selective blocker of mechanosensitive ion channels 08GSM001-00050
Psalmotoxin-1 / PcTx1 ASIC1a selective blocker 13PCT001-00100
MitTx MitTx toxin – ASIC1a/1b agonist MTX002
Mambalgin-1 ASIC1a & 1b channel blocker MAM001-50010
APETx2 ASIC3 selective inhibitor 07APE002-00100
αC-Conotoxin-PrXA Selective blocker of muscular nACh receptors 13CON016-00100
α-conotoxin-PeIA Discriminates between α9α10 and α7 nAChRs 13CON017-00100
α-conotoxin-MI Blocks the α/δ site of the muscle-type nAChR 08CON012-00500
α-conotoxin-IMI α7 nAChR selective blocker 08CON011-00500
α-conotoxin-GID Blocker of α3β2, α7 and α4β2 nAChRs CON019-50100
α-conotoxin-GI Blocks the α/δ site of the muscle-type nAChR 08CON015-00500
α-Conotoxin PIA CON023
α-Conotoxin BuIA CON024-00100
Waglerin-1-FAM Waglerin-1 blocks muscle nAChRs WAG002-01000
Waglerin-1 Waglerin-1 blocks muscle-type nAChRs 12WAG001-01000
alpha-cobratoxin α7 nicotinic acetylcholine receptor (nAChR) antagonist CBT001
GaTx2 Selective blocker of ClC2 (CLCN2) chloride channels 10GTX002-00100

沪公网安备 31011202007337号