Anti-Androgen Receptor (AR-V7 specific) Rabbit Monoclonal Antibody, Clone RM7

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产品名称: Anti-Androgen Receptor (AR-V7 specific) Rabbit Monoclonal Antibody, Clone RM7

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Anti-Androgen Receptor (AR-V7 specific) Rabbit Monoclonal Antibody, Clone RM7

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Product Details
Product Name	Anti-Androgen Receptor (AR-V7 specific) Rabbit Monoclonal Antibody [RM7]
Product Description	Rabbit monoclonal to Androgen Receptor (AR-V7 specific), ARv7 Splice Variant
Catalog No.	31-1109-00
Clone Name	RM7
Product Data Sheet	Anti-Androgen Receptor (AR-V7 specific) Rabbit Monoclonal Antibody Data Sheet RM7
Specificity	RM7 reacts to androgen receptor splice variant 7 (AR-V7). No cross reactivity with wild type androgen receptor.
Immunogen	A peptide corresponding to AR splice variant 7
Application	Immunohistochemistry Immunocytochemistry Immunoprecipitation Western Blot Chromatin IP Circulating Tumor Cells
Species Reactivity	Human
Conjugate	None
Intended Use	Research Use Only
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Properties
Form	Liquid
Storage Instructions	Store at -20.0°C
Stability	Stable for 1 Year at -20.0°C from date of receipt
Storage Buffer	50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Volume/Item Size	100ul
Purity	Protein A affinity purified from an animal origin–free culture supernatant
Clone Type	Monoclonal
Isotype	Rabbit IgG
Usage	Immunohistochemistry (IHC): 1:500 – 1:1000 dilution; Immunocytochemistry (ICC): 1:100 – 1:1000 dilution; Western Blot (WB): 1:500 – 1:1000 dilution.
References for ARv7 Splice Variant antibody [RM7]	Miao L et al. Disrupting androgen receptor signaling induces Snail-mediated epithelial-mesenchymal plasticity in prostate cancer. Cancer Res.10.1158/0008-5472.CAN-16-2169. WB; Human. Read more (PubMed: 28302679)
Protocols	ARv7 ICC Protocol ARv7 IHC Protocol
Product Images
	Western Blot analysis of 22RV1, DU145, and PC-3 whole cell lysates, using anti-AR-V7 rabbit monoclonal Antibody Clone RM7, showed endogenous AR-V7 expressed in 22RV1 cells.
	Immunocytochemical staining of 22RV1 and PC-3 cells,using anti-AR-V7 rabbit monoclonal Antibody Clone RM7 (red). Actin filaments have been labeled with fluorescein phalloidin (green).
	Immunohistochemical staining of formalin fixed and paraffin embedded 22RV1, DU145 sections.
	Immunohistochemical staining of formalin fixed and paraffin embedded (FFPE) bone metastasis prostate cancer. Clinically validated to be Positive for ARv7. Image courtesy of Dr. Stephen Plymate, University of Washington, Washington, US
	Immunohistochemical staining of formalin fixed and paraffin embedded (FFPE) bone metastasis prostate cancer. Clinically validated to be Negative for ARv7. Image courtesy of Dr. Stephen Plymate, University of Washington, Washington, US

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