TA1537 - S.typhimurium Tester Strain for Ames Test:
 

• for the detection of genotoxic chemicals according to OECD 471 
• for the screening of chemical, pharmaceutical or cosmetic compounds in a miniaturized assay system (Ames MPF)

Characteristics

• Mutation: hisC3076
• Type: Frameshifts
• Target: +1 frameshift near C-C-C 
• rfa Mutation: defective lipopolysaccharide (LPS) layer
• uvrB Mutation: Eliminates the accurate excision repair mechanism
• pKM101 R-Factor Plasmid: No Plasmid, not Ampicillin Resistent
• Shipment with ice bricks at room temperature from Germany

Safety

The strains of Salmonella typhimurium and Escherichia coli are classified under the lowest level of risk, groupe 1 in Switzerland, Biostoff S1 in Germany, ... They are considered as non-GMOs because they can be constructed by self-cloning or are naturally occurring bacterial strains. They do not disturb the biological diversity.