Art. No.: N32-233-Y
Ready to use Estrogen Receptor Transactivation Test Kit for Identifying Estrogen Receptor Agonists in endocrine disrupting chemicals, agrochemicals, cosmetics (EDC's) or in waste water. In compliance with OECD Guideline TG455.
Characteristics
Many endocrine disrupting chemicals adversely impact the estrogen signaling by interacting with estrogen receptors. The receptors show ligand selectivity and target gene regulation, they modulate metabolic enzymes that are critical for normal estrogen synthesis and metabolism. Typical EDC's are e.g. phytoestrogens, bisphenolics, and organochlorine pesticides. Many endocrine discrupting chemicals act through multiple mechanisms and therefore biological effects of EDCs need to be carefully interpreted.
Short Protocol
Leaflets
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