Service anayltics with in Vitro Mammalian Cell Micronucleus Test (MNT) according to OECD487 under GLP and non GLP conditions. The MNT is used for the  screening of test compounds for gentoxic activity by measuring micronuclei formed during exposure to test compound. The test is used for  in vitro toxicological risk assessment of chemicals, pesticides, cosmetics, plant extracts.

Characteristics

• The test can be performed in primary human peripheral blood lymphocytes (HPBLs) or in TK6 cells, translocation of the test system to other cell lines is also offered.
• The experiments are performed in the presence and absence of post mitochondrial supernatant (S9) 
• Qualitative and quantitative approach
• Can be combined with telomer and centromer staining for increased sensitivity 
• Allows discrimination between aneugenic and clastogenic compounds if combined with Telomer and Centromer Staining

  Leaflets

   Service Analytics Leaflet

   Service Analytics for Genotoxicity Leaflet