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yc-1 hif-1 inhibitor , reduced whole kidney glomerular hypertrophy

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产品名称: yc-1 hif-1 inhibitor , reduced whole kidney glomerular hypertrophy
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简单介绍

CAS:170632-47-0Formula:C19H16N2O2MW:304.4Appearance:Off-WhitetoYellowSolidPurity:98%


yc-1 hif-1 inhibitor , reduced whole kidney glomerular hypertrophy  的详细介绍
A direct activator of soluble Guanylyl Cyclase (sGC), independent of Nitric Oxide.Involvement of P2X7 Receptors A novel mode of action of YC-1 in HIF inhibition: stimulation of FIH-dependent p300 dissociation from HIF-1,

Additional Information

Synonyms3-(5'-hydroxymethyl-2'furyl)-1-benzyl indazole
Product #Y-1000
CAS #170632-47-0
Chemical Name3-(5'-hydroxymethyl-2'furyl)-1-benzyl indazole
FormulaC19H16N2O2
MW304.4
AppearanceOff-White to Yellow Solid
Purity98%
SolubilityDMSO
Melting Point110-113 °C
Storage Temp+4°C
Therapeutic AreaOncological Disorders
UseYC-1 is a potential anticancer drug targeting hypoxia-inducible factor 1

Additional Information

MDL NumberMFCD06407798
ChemACXX1206446-5
InChIInChI=1S/C19H16N2O2/c22-13-15-10-11-18(23-15)19-16-8-4-5-9-17(16)21(20-19)12-14-6-2-1-3-7-14/h1-11,22H,12-13H2
SMILESc1ccc(cc1)Cn2c3ccccc3c(n2)c4ccc(o4)CO
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