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yc-1 hif-1 inhibitor , reduced whole kidney glomerular hypertrophy
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yc-1 hif-1 inhibitor , reduced whole kidney glomerular hypertrophy
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简单介绍
CAS:170632-47-0Formula:C19H16N2O2MW:304.4Appearance:Off-WhitetoYellowSolidPurity:98%
yc-1 hif-1 inhibitor , reduced whole kidney glomerular hypertrophy
的详细介绍
A direct activator of soluble Guanylyl Cyclase (sGC), independent of Nitric Oxide.Involvement of P2X7 Receptors A novel mode of action of YC-1 in HIF inhibition: stimulation of FIH-dependent p300 dissociation from HIF-1,
Additional Information
Synonyms
3-(5'-hydroxymethyl-2'furyl)-1-benzyl indazole
Product #
Y-1000
CAS #
170632-47-0
Chemical Name
3-(5'-hydroxymethyl-2'furyl)-1-benzyl indazole
Formula
C
19
H
16
N
2
O
2
MW
304.4
Appearance
Off-White to Yellow Solid
Purity
98%
Solubility
DMSO
Melting Point
110-113 °C
Storage Temp
+4°C
Therapeutic Area
Oncological Disorders
Use
YC-1 is a potential anticancer drug targeting hypoxia-inducible factor 1
Additional Information
MDL Number
MFCD06407798
ChemACX
X1206446-5
InChI
InChI=1S/C19H16N2O2/c22-13-15-10-11-18(23-15)19-16-8-4-5-9-17(16)21(20-19)12-14-6-2-1-3-7-14/h1-11,22H,12-13H2
SMILES
c1ccc(cc1)Cn2c3ccccc3c(n2)c4ccc(o4)CO
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yc-1 hif-1 inhibitor , reduced whole kidney glomerular hypertrophy
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