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WY-14,643 | CAS [50892-23-4] | Pirinixic acid | A.G. Scientific, Inc

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产品名称: WY-14,643 | CAS [50892-23-4] | Pirinixic acid | A.G. Scientific, Inc
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简单介绍

CAS:50892-23-4Formula:C14H14ClN3O2SMW:323.8Appearance:WhiteSolidPurity:98%


WY-14,643 | CAS [50892-23-4] | Pirinixic acid | A.G. Scientific, Inc  的详细介绍

WY-14,643 is a widely used activator of peroxisome proliferator activator receptors (PPARs). WY-14,643 (PPAR activator) belong to the family of nuclear hormone receptor transcription factors.Coordinate Transcriptional Repression of Liver Fatty Acid-binding Protein and Microsomal Triglyceride Transfer Protein Blocks Hepatic Very Low Density Lipoprotein Secretion without Hepatosteatosis.

Additional Information

SynonymsPirinixic acid
Product #W-1026
CAS #50892-23-4
Chemical Name(4-Chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl)thioacetic acid
FormulaC14H14ClN3O2S
MW323.8
AppearanceWhite Solid
Purity98%
SolubilitySoluble in DMSO, Ethanol, Methanol, alsoPBS.
Storage TempRoom Temp
Therapeutic AreaCardiological Disorders
UsePeroxisome proliferator-activated receptor alpha (PPARa) agonist for prevention of severe cardiac dysfunction, cardiomyopathy and heart failure

Additional Information

MDL NumberMFCD00191335
ChemACXX1005393-1
InChIInChI=1S/C14H14ClN3O2S/c1-8-4-3-5-10(9(8)2)16-12-6-11(15)17-14(18-12)21-7-13(19)20/h3-6H,7H2,1-2H3,(H,19,20)(H,16,17,18)
SMILESCc1cccc(c1C)Nc2cc(nc(n2)SCC(=O)O)Cl
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