Vinorelbine Tartrate

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产品名称: Vinorelbine Tartrate

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简单介绍

CAS:125317-39-7Formula:C45H54N4O8.C8H12O12MW:1079.11Appearance:Off-whitesolidPurity:≥98%byHPLC

Vinorelbine Tartrate 的详细介绍

A semi-synthetic vinca alkaloid that displays potent anti-mitotic and anti-tumor properties. Its main mechanism of action is thought to be inhibition of microtubule dynamics, which results in mitotic arrest and eventual cell death. Acts as a microtubule destabilizing agent. At high concentrations, it stimulates microtubule depolymerization and mitotic spindle destruction. At lower clinically relevant concentrations, vinorelbine blocks mitotic progression. Its main targets are tubulin and microtubules. Unlike the taxanes, which bind poorly to soluble tubulin, vinorelbine can bind both soluble and microtubule-associated tubulin.

Additional Information

Product #	V-2479
CAS #	125317-39-7
Chemical Name	3′,4′-Didehydro-4′-deoxy-C′-norvincaleukoblastine [R-(R,R)-2-3-dihydroxybutanedioate (1:2)salt], 5′-Noranhydrovinoblastine tartrate, KW-2307, NVB, Navelbine tartrate
Formula	C₄₅H₅₄N₄O₈.C₈H₁₂O₁₂
MW	1079.11
Appearance	Off-white solid
Purity	≥98% by HPLC
Solubility	Soluble in Water (~ 10 mg/ml)
Storage Temp	-20°C

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