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Validamycin A
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产品名称:
Validamycin A
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简单介绍
CAS:37248-47-8Formula:C20H35NO13MW:497.5Appearance:WhitesolidPurity:>95%byHPLC
Validamycin A
的详细介绍
*Please inquire the availability for this product. Validamycin A is the major analogue of a family of cyclitol disaccharides isolated from Streptomyces hygroscopicus var. limoneus by researchers at Takeda in 1970. Although commonly regarded as an aminoglycoside, validamycin shares little in common with conventional aminoglycosides such as streptomycin and gentamicin. Validamycin A is a potent antifungal agent and is used to control fungi in crop production. Validamycin A acts as a potent inhibitor of trehalase, an important enzyme in carbohydrate storage and ultilisation in fungi.
Additional Information
Synonyms
Antibiotic T 7545A
Product #
V-2489
CAS #
37248-47-8
Chemical Name
(1S-(1ALPHA,4ALPHA,5BETA,6ALPHA))-1,5,6-TRIDEOXY-3-O-BETA-D-GLUCOPYRANOSYL-5-(HYDROXYMETHYL)-1-((4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)-2-CYCLOHEXEN-1-YL) AMINO)-D-CHIRO-INOSITOL
Formula
C20H35NO13
MW
497.5
Appearance
White solid
Purity
>95% by HPLC
Solubility
Soluble in water, methanol, DMSO, DMF, ethanol (slightly), and acetone (slightly) Insoluble in ethyl acetate, and diethyl ether
Melting Point
130-135 °C
Storage Temp
-20
Use
Validamycin A is a potent antifungal agent and is used to control fungi in crop production
Additional Information
MDL Number
MFCD09028089
InChI
InChI=1S/C20H35NO13/c22-3-6-1-8(12(26)15(29)11(6)25)21-9-2-7(4-23)19(17(31)13(9)27)34-20-18(32)16(30)14(28)10(5-24)33-20/h1,7-32H,2-5H2/t7-,8+,9+,10-,11+,12+,13+,14-,15+,16+,17-,18-,19-,20+/m1/s1
SMILES
C1[C@@H]([C@H]([C@@H]([C@H]([C@H]1N[C@H]2C=C([C@@H]([C@@H]([C@H]2O)O)O)CO)O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)CO
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