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Validamycin A

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产品名称: Validamycin A
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简单介绍

CAS:37248-47-8Formula:C20H35NO13MW:497.5Appearance:WhitesolidPurity:>95%byHPLC


Validamycin A  的详细介绍
*Please inquire the availability for this product. Validamycin A is the major analogue of a family of cyclitol disaccharides isolated from Streptomyces hygroscopicus var. limoneus by researchers at Takeda in 1970. Although commonly regarded as an aminoglycoside, validamycin shares little in common with conventional aminoglycosides such as streptomycin and gentamicin. Validamycin A is a potent antifungal agent and is used to control fungi in crop production. Validamycin A acts as a potent inhibitor of trehalase, an important enzyme in carbohydrate storage and ultilisation in fungi.

Additional Information

SynonymsAntibiotic T 7545A
Product #V-2489
CAS #37248-47-8
Chemical Name(1S-(1ALPHA,4ALPHA,5BETA,6ALPHA))-1,5,6-TRIDEOXY-3-O-BETA-D-GLUCOPYRANOSYL-5-(HYDROXYMETHYL)-1-((4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)-2-CYCLOHEXEN-1-YL) AMINO)-D-CHIRO-INOSITOL
FormulaC20H35NO13
MW497.5
AppearanceWhite solid
Purity>95% by HPLC
SolubilitySoluble in water, methanol, DMSO, DMF, ethanol (slightly), and acetone (slightly) Insoluble in ethyl acetate, and diethyl ether
Melting Point130-135 °C
Storage Temp-20
UseValidamycin A is a potent antifungal agent and is used to control fungi in crop production

Additional Information

MDL NumberMFCD09028089
InChIInChI=1S/C20H35NO13/c22-3-6-1-8(12(26)15(29)11(6)25)21-9-2-7(4-23)19(17(31)13(9)27)34-20-18(32)16(30)14(28)10(5-24)33-20/h1,7-32H,2-5H2/t7-,8+,9+,10-,11+,12+,13+,14-,15+,16+,17-,18-,19-,20+/m1/s1
SMILESC1[C@@H]([C@H]([C@@H]([C@H]([C@H]1N[C@H]2C=C([C@@H]([C@@H]([C@H]2O)O)O)CO)O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)CO
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