USP14 Inhibitor, IU1

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产品名称: USP14 Inhibitor, IU1

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简单介绍

CAS:314245-33-5Formula:C18H21FN2OMW:300.37Appearance:Whitetooff-whiteSolidPurity:98%byHPLC

USP14 Inhibitor, IU1 的详细介绍

A cell-permeable, reversible and selective inhibitor of the deubiquitinating activity of human USP14 (IC= 4-5 M). IU1 promotes cell survival during proteotoxic stress and selectively stimulates ubiquitin-dependent protein degradation in vitro at 34M.

Additional Information

Synonyms	1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-ethanone
Product #	U-2474
CAS #	314245-33-5
Chemical Name	1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-ethanone
Formula	C₁₈H₂₁FN₂O
MW	300.37
Appearance	White to off-white Solid
Purity	98% by HPLC
Solubility	DMSO (~20 mg/ml)
Storage Temp	-20°C
Use	IU1 is an inhibitor of USP14, a deubiquitinating enzyme associated with the proteasome

Additional Information

MDL Number	MFCD01917473
ChemACX	X2815842-9
InChI	InChI=1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8,11H,3-4,9-10,12H2,1-2H3
SMILES	Cc1cc(c(n1c2ccc(cc2)F)C)C(=O)CN3CCCC3

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