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Tyrothricin
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产品名称:
Tyrothricin
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简单介绍
CAS:1404-88-2Formula:C65H85N11O13MW:1228.43Appearance:WhitesoidPurity:>95%compositepurity(basedon80%tyrocidineand20%Gramicidincomplexes)
Tyrothricin
的详细介绍
*Please inquire the availability for this product. Tyrothricin is a complex of two unrelated peptide families, gramicidin complex and tyrocidines complex, produced by Bacillus brevis and discovered by Dubos in 1939. Typically, tyrothricin is composed of 20% of the linear pentadecylpeptide gramicidins and 80% of cyclic decapeptide tyrocidines. Both the gramicidins and tyrocidines act by disrupting bacterial cell wall integrity, but by differing mechanisms. Tyrothricin is used clinically for bacterial skin infections in some countries.
Additional Information
Synonyms
Bactralycin, Dermotricine
Product #
T-2671
CAS #
1404-88-2
Formula
C65H85N11O13
MW
1228.43
Appearance
White soid
Purity
>95% composite purity (based on 80% tyrocidine and 20% Gramicidin complexes)
Therapeutic Area
Infectious Diseases
Use
Tyrothricin is a cyclic polypeptide-antibiotic mixture from Bacillus brevis. It is a locally effective antibiotic effective against gram-positive bacteria
Additional Information
MDL Number
MFCD00082120
InChI
InChI=1S/C65H85N11O13/c1-38(2)32-49-60(84)74-52(36-42-20-12-7-13-21-42)65(89)76-31-15-23-53(76)63(87)73-51(34-41-18-10-6-11-19-41)61(85)70-47(33-40-16-8-5-9-17-40)57(81)48(37-54(67)78)71-59(83)46(28-29-55(79)80)68-50(35-43-24-26-44(77)27-25-43)62(86)75-56(39(3)4)64(88)69-45(22-14-30-66)58(82)72-49/h5-13,16-21,24-27,38-39,45-53,56,68,77H,14-15,22-23,28-37,66H2,1-4H3,(H2,67,78)(H,69,88)(H,70,85)(H,71,83)(H,72,82)(H,73,87)(H,74,84)(H,75,86)(H,79,80)/t45-,46-,47+,48-,49-,50-,51-,52+,53-,56-/m0/s1
SMILES
CC(C)C[C@H]1C(=O)N[C@@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](C(=O)[C@@H](NC(=O)[C@@H](N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCCN)C(C)C)Cc3ccc(cc3)O)CCC(=O)O)CC(=O)N)Cc4ccccc4)Cc5ccccc5)Cc6ccccc6
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