TM-2-51 | HDAC8 activator

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产品名称: TM-2-51 | HDAC8 activator

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简单介绍

CAS:4921-82-8Formula:C14H12N2OSMW:256.32Appearance:Off-whitesolidPurity:98%byTLCNMR(Conforms)

TM-2-51 | HDAC8 activator 的详细介绍

TM-2-51 (4921-82-8) is a highly potent and isozyme selective activator of recombinant HDAC8. Increases the activity of HDAC8 by a factor of 12 at 10 μM. No activation of other HDACs is observed. TM-2-51 rescues the activity of catalytically compromised HDAC8 mutants in vitro.

Additional Information

Product #	T-2823
CAS #	4921-82-8
Chemical Name	1-Benzoyl-3-phenyl-2-thiourea
Formula	C₁₄H₁₂N₂O_S
MW	256.32
Appearance	Off-white solid
Purity	98% by TLC NMR (Conforms)
Solubility	Soluble in DMSO (greater than 50 mg/ml) or in Ethanol (up to 8 mg/ml).
Storage Temp	-20°
Use	HDAC8 activator

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