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Tiamulin

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产品名称: Tiamulin
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简单介绍

CAS:55297-95-5Formula:C28H47NO4SMW:493.7Appearance:EvaporatedresinPurity:>98%byHPLC


Tiamulin  的详细介绍

*Please inquire the availability for this product. Tiamulin is a semi–synthetic analogue of pleuromutilin in which the hydroxyacetyl side chain is replaced with a larger diethylaminoethylthioacetyl moiety, providing greater hydrophobicity and an ionisable group for salt formation and greater water solubility. Tiamulin is a potent and highly selective antibiotic active against a range of Gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action. Like pleuromutilin, it inhibits protein synthesis by binding to domain V of 23S rRNA.

Additional Information

Product #T-2633
CAS #55297-95-5
FormulaC28H47NO4S
MW493.7
AppearanceEvaporated resin
Purity>98% by HPLC
Melting Point233.89 °C
Storage Temp4°C
UseTiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine

Additional Information

MDL NumberMFCD01672098
InChIInChI=1S/C28H47NO4S/c1-8-26(6)17-22(33-23(31)18-34-16-15-29(9-2)10-3)27(7)19(4)11-13-28(20(5)25(26)32)14-12-21(30)24(27)28/h8,19-20,22,24-25,32H,1,9-18H2,2-7H3/t19-,20+,22-,24+,25+,26-,27+,28+/m1/s1
SMILESCCN(CC)CCSCC(=O)O[C@@H]1C[C@@]([C@H]([C@@H]([C@@]23CC[C@H]([C@@]1([C@@H]2C(=O)CC3)C)C)C)O)(C)C=C
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