Thiamphenicol

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产品名称: Thiamphenicol

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简单介绍

CAS:15318-45-3Formula:C12H15Cl2NO5SMW:356.2Appearance:WhitesolidPurity:>99%byHPLC

Thiamphenicol 的详细介绍

*Please inquire the availability for this product. Thiamphenicol is a semi-synthetic chloramphenicol prepared by total synthesis from thiophenol in which the nitro moiety of chloramphenicol is replaced by a methylsulphone, first synthesised at Sterling Winthrop in 1952. Thiamphenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Thiamphenicol acts by binding to the 23S sub-unit of the 50S ribosome inhibiting protein synthesis. Thiamphenicol has been extensively studied with over 800 literature citations.

Additional Information

Synonyms	Thiocymetin, Thiophenicol, Win 5062-2, NSC 522822
Product #	T-2623
CAS #	15318-45-3
Formula	C12H15Cl2NO5S
MW	356.2
Appearance	White solid
Purity	>99% by HPLC
Solubility	Soluble in DMSO, Ethanol and Water
Storage Temp	4°C
Therapeutic Area	Infectious Diseases
Use	Thiamphenicol is used for the treatment of sexually transmitted infections

Additional Information

MDL Number	MFCD00467983
InChI	InChI=1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1
SMILES	CS(=O)(=O)c1ccc(cc1)[C@H]([C@@H](CO)NC(=O)C(Cl)Cl)O

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