TGX-221

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产品名称: TGX-221

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简单介绍

CAS:663619-89-4Formula:C21H24N4O2MW:364.44Appearance:WhiteSolidPurity:98%byHPLC

TGX-221 的详细介绍

Cell-permeable. A potent, selective and ATP-competitive inhibitor of PI 3-kinase (IC= 5 nM for p110). Inhibits other PI3K isoforms at higher concentrations (IC= 0.1 M for p110, 5 M for p110, and 3.5 M for p110).

Additional Information

Synonyms	7-Methyl-2-(morpholin-4-yl)-9-(1-phenylaminoethyl)-pyrido[1,2-a]-pyrimidin-4-one
Product #	T-2460
CAS #	663619-89-4
Chemical Name	(±)-7-Methyl-2-(morpholin-4-yl)-9-(1-phenylaminoethyl)-pyrido[1,2-a]-pyrimidin-4-one
Formula	C₂₁H₂₄N₄O₂
MW	364.44
Appearance	White Solid
Purity	98% by HPLC
Solubility	DMSO (10 mg/ml) or Ethanol (5 mg/ml)
Storage Temp	-20°C

Additional Information

MDL Number	MFCD11113209
ChemACX	X1600331-3
InChI	InChI=1S/C21H24N4O2/c1-15-12-18(16(2)22-17-6-4-3-5-7-17)21-23-19(13-20(26)25(21)14-15)24-8-10-27-11-9-24/h3-7,12-14,16,22H,8-11H2,1-2H3
SMILES	CC1=CN2C(=O)C=C(N=C2C(=C1)C(C)NC3=CC=CC=C3)N4CCOCC4

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