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Tetrahydrouridine

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产品名称: Tetrahydrouridine
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简单介绍

CAS:18771-50-1Formula:C9H16N2O6MW:248.23Appearance:Off-WhiteSolidPurity:~80%byTLC


Tetrahydrouridine  的详细介绍
A competitive cytidine deaminase inhibitor and multidrug resistance modulator. Makes tumor cells more sensitive to radiation therapy making it useful for cancer treatment

Additional Information

SynonymsTHU
Product #T-2455
CAS #18771-50-1
Chemical Name1-[(2R,3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-4-HYDROXY-1,3-DIAZINAN-2-ONE
FormulaC9H16N2O6
MW248.23
AppearanceOff-White Solid
Purity~80% by TLC
SolubilitySoluble in H2O (200 mg/ml) or MeOH (50 mg/ml)
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseA CDD inhibitor which may prevent growth of CDA-expressing tumors

Additional Information

MDL NumberMFCD00063468
ChemACXX1497824-4
InChIInChI=1S/C9H16N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4-8,12-15H,1-3H2,(H,10,16)
SMILESC1CN(C(=O)NC1O)C2C(C(C(O2)CO)O)O
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