Tenofovir disoproxil fumarate

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产品名称: Tenofovir disoproxil fumarate

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简单介绍

CAS:202138-50-9Formula:C19H30N5O10P.C4H4O4MW:653.51Appearance:WhiteSolidPurity:98%byHPLC

Tenofovir disoproxil fumarate 的详细介绍

A water-soluble diester prodrug of the active ingredient Tenofovir, that belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (NtRTIs), which block reverse transcriptase, an enzyme crucial to viral production in HIV-infected people.

Additional Information

Synonyms	9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)-phosphinyl)methoxy)propyl)adenine fumarate
Product #	T-2454
CAS #	202138-50-9
Chemical Name	9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)-phosphinyl)methoxy)propyl)adenine fumarate
Formula	C₁₉H₃₀N₅O₁₀P. C₄H₄O₄
MW	653.51
Appearance	White Solid
Purity	98% by HPLC
Solubility	Soluble in Water (>10 mg/ml)
Melting Point	113-115 °C
Storage Temp	+4°C
Therapeutic Area	Infectious Diseases
Use	Viread (tenofovir) is an antiviral medication that prevents human immunodeficiency virus (HIV) or hepatitis B

Additional Information

MDL Number	MFCD08141829
ChemACX	X1511964-7
InChI	InChI=1S/C19H30N5O10P.C4H4O4/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24;5-3(6)1-2-4(7)8/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22);1-2H,(H,5,6)(H,7,8)/b;2-1+/t14-;/m1./s1
SMILES	C[C@H](Cn1cnc2c1ncnc2N)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C.C(=C/C(=O)O)C(=O)O

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