SU6668

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产品名称: SU6668

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简单介绍

CAS:210644-62-5Formula:C18H18N2O3MW:310.35Appearance:YellowtoDarkyellowSolidPurity:98%

SU6668 的详细介绍

Cell-permeable. A potent and ATP-competitive inhibitor of PDGF, VEGF and FGF receptor tyrosine kinases (RTKs) with ICvalues of 0.06, 2.43, 3.04 and 100M at PDGFR, VEGFR2. FGFR1 and EGFR respectively. Acts as a potent antiangiogenic and antitumor agent.

Additional Information

Synonyms	PDGFR Tyrosine Kinase Inhibitor VI
Product #	S-2120
CAS #	210644-62-5
Chemical Name	2,4-DIMETHYL-5-[(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)METHYL]-PYRROLE-3-PROPANOIC ACID
Formula	C₁₈H₁₈N₂O₃
MW	310.35
Appearance	Yellow to Dark yellow Solid
Purity	98%
Solubility	DMSO (~100 mM)
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	A potent ATP-competitive inhibitor against tyrosine kinases.Acts as a potent antiangiogenic and antitumor agent

Additional Information

MDL Number	MFCD09743433
ChemACX	X1671181-8
InChI	InChI=1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)/b14-9-
SMILES	Cc1c(c([nH]c1/C=C2/c3ccccc3NC2=O)C)CCC(=O)O

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