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SU 5402 | CAS# [215543-92-3] | Inhibitor of FGFR | A.G. Scientific

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产品名称: SU 5402 | CAS# [215543-92-3] | Inhibitor of FGFR | A.G. Scientific
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简单介绍

CAS:215543-92-3Formula:C17H16N2O3MW:296.32Appearance:YellowSolidPurity:97%byHPLC


SU 5402 | CAS# [215543-92-3] | Inhibitor of FGFR | A.G. Scientific  的详细介绍
A potent and selective inhibitor of fibroblast growth factor receptor (FGFR) (IC50 = 0.03 M for FGFR1) and vascular endothelial growth factor receptors (VEGFR) (IC50 = 0.02 M for VEGFR2).

Additional Information

Synonyms2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-meth yl-1H-pyrrole-3-propanoic acid
Product #S-2116
CAS #215543-92-3
Chemical Name2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-meth yl-1H-pyrrole-3-propanoic acid
FormulaC17H16N2O3
MW296.32
AppearanceYellow Solid
Purity97% by HPLC
SolubilitySoluble in DMSO (100mM)
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseSU 5402 is a fibroblast growth factor receptor (FGFR)-specific tyrosine kinase inhibitor use in Multiple myeloma

Additional Information

MDL NumberMFCD08235144
ChemACXX1498370-5
InChIInChI=1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8-
SMILESCc1c[nH]c(c1CCC(=O)O)/C=C2/c3ccccc3NC2=O
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