SU 4984

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产品名称: SU 4984

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简单介绍

Formula:C20H19N3O2MW:333.4Appearance:OrangetoredcrystallineSolidPurity:98%

SU 4984 的详细介绍

Inhibitor of tyrosine kinase activity of fibroblast growth factor receptor 1 (FGFR1). Inhibits FGF-induced tyrosine phosphorylation of ERK1 and ERK2 (IC50=20-4M) and the tyrosine phosphorylation of the PDGF receptor and the insulin receptor. Does not inhibit the kinase activity of the EGF receptor.

Additional Information

Synonyms	3[4-(1-Formylpiperazin-4-yl)benzylidenyl]-2-indolinone
Product #	S-1126
Chemical Name	3[4-(1-FORMYLPIPERAZIN-4-YL)BENZYLIDENYL]-2-INDOLINONE
Formula	C₂₀H₁₉N₃O₂
MW	333.4
Appearance	Orange to red crystalline Solid
Purity	98%
Solubility	Soluble in DMSO
Melting Point	276°C
Storage Temp	-20°C

Additional Information

MDL Number	MFCD08443934
ChemACX	X1498188-7
InChI	InChI=1S/C20H19N3O2/c24-14-22-9-11-23(12-10-22)16-7-5-15(6-8-16)13-18-17-3-1-2-4-19(17)21-20(18)25/h1-8,13-14H,9-12H2,(H,21,25)/b18-13-
SMILES	C1CN(CCN1C=O)C2=CC=C(C=C2)/C=C/3C4=CC=CC=C4NC3=O

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