Stat3 Activation Inhibitor, SPI

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产品名称: Stat3 Activation Inhibitor, SPI

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简单介绍

Formula:C146H238N40O42.C2HF3O2MW:3225.74.114.02Appearance:LyophilizedSolidPurity:95%byHPLC

Stat3 Activation Inhibitor, SPI 的详细介绍

Cell-permeable. A potent and selective inhibitor of Stat3 SH2 domain:pTyr interactions; also disrupts the binding of Stat3 to the IL-6R/gp130 peptide, GpYLPQTVNH2 and induces antitumor effects in vitro.

Additional Information

Synonyms	FISKERERAILSTKPPGTFLLRFSESSK
Product #	S-2443
Chemical Name	FISKERERAILSTKPPGTFLLRFSESSK; H-PHE-ILE-SER-LYS-GLU-ARG-GLU-ARG-ALA-ILE-LEU-SER-THR-LYS-PRO-PRO-GLY-THR-PHE-LEU-LEU-ARG-PHE-SER-GLU-SER-SER-LYS-OH
Formula	C₁₄₆H₂₃₈N₄₀O₄₂.C₂HF₃O₂
MW	3225.74. 114.02
Appearance	Lyophilized Solid
Purity	95% by HPLC
Solubility	Soluble in H₂O
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	A potent and selective inhibitor of Stat3 SH2 domain:pTyr interactions; also disrupts the binding of Stat3 to the IL-6R/gp130 peptide, GpYLPQTVNH? and induces antitumor effects

Additional Information

Peptide Sequence	H-PHE-ILE-SER-LYS-GLU-ARG-GLU-ARG-ALA-ILE-LEU-SER-THR-LYS-PRO-PRO-GLY-THR-PHE-LEU-LEU-ARG-PHE-SER-GLU-SER-SER-LYS-OH

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