SR1001

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产品名称: SR1001

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简单介绍

Formula:C15H13F6N3O4S2MW:477.4Appearance:Cream-coloredsolidPurity:≥98%byTLCandNMR

SR1001 的详细介绍

SR1001 is high affinity synthetic ligand specific to both retinoic acid-related orphan receptors ɑ (RORɑ) and γt (RORγt). SR1001 inhibits interleukin-17 (TH17) cell differentiation and function as well as suppressing the clinical severity of autoimmune disease in mice. It is cell-permeable.

Additional Information

Product #	S-2442
Chemical Name	N-(5-(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)sulphamoyl)-4-methylthiazol-2-yl)acetamide
Formula	C₁₅H₁₃F₆N₃O₄S₂
MW	477.4
Appearance	Cream-colored solid
Purity	≥98% by TLC and NMR
Solubility	soluble in DMSO (10 mg/ml)
Storage Temp	-20°C

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