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AGScientific
SH-6
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产品名称:
SH-6
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简单介绍
Formula:C28H57O9PMW:568.7Appearance:WhitetoOff-WhiteSolidPurity:98%
SH-6
的详细介绍
Inhibitor of Akt (PKB) activation without affecting activation of the upstream kinase PDK-1, or other kinases downstream of Ras such as MAPK. Induces apoptosis and kills a variety of cancer cell lines.
Additional Information
Synonyms
D-2,3-Dideoxy-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate]
Product #
S-2026
Chemical Name
D-2,3-Dideoxy-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate]
Formula
C
28
H
57
O
9
P
MW
568.7
Appearance
White to Off-White Solid
Purity
98%
Solubility
Soluble in DMSO, Methanol or Water.
Storage Temp
+4°C
Therapeutic Area
Oncological Disorders
Use
SH-6 is an inhibitor of Akt (PKB) activation without affecting activation of the upstream kinase PDK-1, or other kinases downstream of Ras such as MAPK. SH-5 induces apoptosis and kills a variety of cancer cell
Additional Information
MDL Number
MFCD06412428
ChemACX
X1497828-2
InChI
InChI=1S/C28H57O9P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21-35-22-24(34-2)23-36-38(32,33)37-26-20-19-25(29)27(30)28(26)31/h24-31H,3-23H2,1-2H3,(H,32,33)/t24-,25-,26-,27+,28+/m1/s1
SMILES
CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OC1CCC(C(C1O)O)O)OC
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