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Sancycline hydrochloride

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产品名称: Sancycline hydrochloride
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简单介绍

CAS:6625-20-3Formula:C21H23ClN2O7MW:450.9Appearance:YellowtoorangesolidPurity:>98%byHPLC


Sancycline hydrochloride  的详细介绍
*Please inquire the availability for this product. Sancycline hydrochloride is the hydrochloride salt of a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of declomycin, first reported in 1962. As the simplest of the early tetracyclines, sancycline was the first to be totally synthesised by Conover and co-workers. Like other tetracyclines, sancycline acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.

Additional Information

Synonyms6-Demethyl-6-deoxytetracycline hydrochloride, NSC 51812
Product #S-2753
CAS #6625-20-3
FormulaC21H23ClN2O7
MW450.9
AppearanceYellow to orange solid
Purity>98% by HPLC
SolubilitySoluble in Methanol
Melting Point224-2280°C
Storage Temp-20°C
Therapeutic AreaInfectious Diseases
UseSancycline Hydrochloride is a semi-synthetic antibiotic

Additional Information

MDL NumberMFCD09842560
InChIInChI=1S/C21H22N2O7.ClH/c1-23(2)15-10-7-9-6-8-4-3-5-11(24)12(8)16(25)13(9)18(27)21(10,30)19(28)14(17(15)26)20(22)29;/h3-5,9-10,15,24,26-27,30H,6-7H2,1-2H3,(H2,22,29);1H/t9-,10-,15-,21-;/m0./s1
SMILESCN(C)[C@H]1[C@@H]2C[C@@H]3Cc4cccc(c4C(=O)C3=C([C@@]2(C(=O)C(=C1O)C(=O)N)O)O)O.Cl
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