Salinomycin

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产品名称: Salinomycin

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简单介绍

CAS:53003-10-4Formula:C42H70O11MW:751Appearance:WhitesolidPurity:>98%byHPLC

Salinomycin 的详细介绍

*Please inquire the availability for this product. Salinomycin is a polyether ionophore with broad spectrum Gram positive and anti-coccidial activity. Salinomycin has a high affinity for monovalent cations, particularly potassium. Salinomycin is used to control coccidia in animals and for growth promotion in ruminants. Recently, salinomycin has been shown to inhibit cancer stem cells and is >100 times more potent than taxol. While the mechanism of action is unknown, it was noted that among the 60,000 compounds screened, another monovalent ionophore, nigericin, and a chloride channel inhibitor, avermectin, were also active.

Additional Information

Synonyms	Eustin, AHR 3096, K 364, 61477
Product #	S-2747
CAS #	53003-10-4
Formula	C42H70O11
MW	751
Appearance	White solid
Purity	>98% by HPLC
Solubility	Ethanol and Chloroform
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	Salinomycin is a polyether ionophore with broad spectrum Gram positive and anti-coccidial activity

Additional Information

MDL Number	MFCD00865281
InChI	InChI=1S/C42H70O11/c1-11-29(38(46)47)31-15-14-23(4)36(50-31)27(8)34(44)26(7)35(45)30(12-2)37-24(5)22-25(6)41(51-37)19-16-32(43)42(53-41)21-20-39(10,52-42)33-17-18-40(48,13-3)28(9)49-33/h16,19,23-34,36-37,43-44,48H,11-15,17-18,20-22H2,1-10H3,(H,46,47)/t23-,24-,25+,26-,27-,28-,29+,30-,31+,32+,33+,34+,36+,37-,39-,40+,41-,42-/m0/s1
SMILES	CC[C@H]([C@H]1CC[C@@H]([C@@H](O1)[C@@H](C)[C@@H]([C@H](C)C(=O)[C@H](CC)[C@@H]2[C@H](C[C@H]([C@]3(O2)C=C[C@H]([C@@]4(O3)CC[C@@](O4)(C)[C@H]5CC[C@@]([C@@H](O5)C)(CC)O)O)C)C)O)C)C(=O)O

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