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Rosuvastatin

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产品名称: Rosuvastatin
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简单介绍

CAS:287714-41-4Formula:C22H28FN3O6SMW:481.54Appearance:Whitetooff-whiteSolidPurity:98%byHPLC


Rosuvastatin  的详细介绍
Rosuvastatin belongs to a class of compounds called statins that is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, an enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis.

Additional Information

Synonyms(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
Product #R-2421
CAS #287714-41-4
Chemical Name(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
FormulaC22H28FN3O6S
MW481.54
AppearanceWhite to off-white Solid
Purity98% by HPLC
SolubilityDMSO
Storage Temp-20°C
Therapeutic AreaCardiological Disorders
UseRosuvastatin belongs to a class of compounds called statins that is used to reduce plasma cholesterol levels and prevent cardiovascular disease

Additional Information

MDL NumberMFCD18783208
ChemACXX1608533-9
InChIInChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1
SMILESCC(C)c1c(c(nc(n1)N(C)S(=O)(=O)C)c2ccc(cc2)F)/C=C/[C@H](C[C@H](CC(=O)O)O)O
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