Ro 61-8048

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产品名称: Ro 61-8048

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简单介绍

CAS:199666-03-0Formula:C17H15N3O6S2MW:421.45Appearance:Off-WhiteSolidPurity:98%byHPLC

Ro 61-8048 的详细介绍

Cell-permeable. A high-affinity small molecule inhibitor of KMO (kynurenine 3-monoxygenase or kynurenine 3-hydroxylase)(K = 4.8 nM, IC= 37 nM).

Synonyms	3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide
Product #	R-2419
CAS #	199666-03-0
Chemical Name	3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide
Formula	C₁₇H₁₅N₃O₆S₂
MW	421.45
Appearance	Off-White Solid
Purity	98% by HPLC
Solubility	DMSO (100 mM) or EtOH (10 mM)
Storage Temp	-20°C
Therapeutic Area	Neurological Disorders
Use	Ro 61-8048 is a potent and competitive kynurenine 3-hydroxylase (KMO) inhibitor in Huntington's disease

MDL Number	MFCD11040807
ChemACX	X1755810-6
InChI	InChI=1S/C17H15N3O6S2/c1-25-15-7-6-13(9-16(15)26-2)28(23,24)19-17-18-14(10-27-17)11-4-3-5-12(8-11)20(21)22/h3-10H,1-2H3,(H,18,19)
SMILES	COc1ccc(cc1OC)S(=O)(=O)Nc2nc(cs2)c3cccc(c3)[N+](=O)[O-]

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