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RK-682
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RK-682
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简单介绍
CAS:332131-32-5Formula:C42H70CaO10MW:775.1Appearance:WhiteSolidPurity:>95%byHPLC
RK-682
的详细介绍
*Please inquire the availability for this product. RK-682 is a dimeric calcium complex of the major analogue of a tetronic acid complex isolated from Streptomyces. Although reported by researchers at RIKEN in 1995, subsequent synthesis in 2001 showed that RK-682 was in fact the calcium complex formed during silica chromatography. Confusion about the structure of RK-682 has lead to the monomeric sub-unit, TAN 1364B (3-hexadecanoyl-5-hydroxymethyltetronic acid) being mis-named as RK-682 by many suppliers. As either the dimer or monomer, RK-682 inhibits protein tyrosine phosphatases, phospoholipase A2, heparinase and HIV-1 protease. However, is unclear whether
biolog
ical activity is due to the monomer (TAN 1364B) or dimeric complex (RK-682).
Additional Information
Synonyms
TAN 1364B, CI 010
Product #
R-2601
CAS #
332131-32-5
Formula
C42H70CaO10
MW
775.1
Appearance
White Solid
Purity
>95% by HPLC
Solubility
Soluble in ethanol, methanol, DMF, and DMSO
Therapeutic Area
Oncological Disorders
Use
RK-682 is a naturally-occurring specific inhibitor of protein tyrosine phosphatase (PTPase)
Additional Information
SMILES
CCCCCCCCCCCCCCCC(=O)C1=C([C@H](OC1=O)CO)O.CCCCCCCCCCCCCCCC(=O)C1=C([C@H](OC1 =O)CO)O.[Ca++]
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