RHC-80267

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产品名称: RHC-80267

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简单介绍

CAS:83654-05-1Formula:C20H34N4O4MW:394.6Appearance:SolidPurity:>98%

RHC-80267 的详细介绍

RHC-80267, an inhibitor of Diacylglycerol lipase (DAG lipase) that is required for 2-arachidonoyl glycerol (2AG) synthesis.

Eicosanoids are signaling molecules made by oxidation of 20-carbon fatty acids. Eicosanoids exercise influence over numerous signaling pathways, primarily in inflammation or immunity, but also, as messengers in the central nervous system.

References:

Shinoda, J., et al. 1997. Arterioscler. Thromb. Vasc. Biol. 17, 295. Shinoda, J., et al. 1997. Eur. J. Endocrinol. 136, 207. Konrad, R.J., et al. 1994. Biochemistry 33, 13284. Mason-Garcia, M., et al. 1992. Am. J. Physiol. 262, C1197. Balsinde, J., et al. 1991. J. Biol. Chem. 266, 15638.

Additional Information

Synonyms	Rhc 80267, RHC-80267, Rg 80267, U 57908
Product #	R-2527
CAS #	83654-05-1
Formula	C₂₀ H₃₄ N₄ O₄
MW	394.6
Appearance	Solid
Purity	>98%
Solubility	soluble in DMSO (9mg/ml) and 100% ethanol (25mg/ml)
Melting Point	118-121°C
Storage Temp	Room Temperature

Additional Information

MDL Number	MFCD00210844
ChemACX	X1192840-2
InChI	InChI=1S/C20H34N4O4/c25-19(27-23-17-11-5-3-6-12-17)21-15-9-1-2-10-16-22-20(26)28-24-18-13-7-4-8-14-18/h1-16H2,(H,21,25)(H,22,26)
SMILES	C1CCC(=NOC(=O)NCCCCCCNC(=O)ON=C2CCCCC2)CC1

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