Reticulol

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产品名称: Reticulol

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简单介绍

CAS:26246-41-3Formula:C11H10O5MW:222.2Appearance:WhitePowderPurity:>95%byHPLC

Reticulol 的详细介绍

*Please inquire the availability for this product. Reticulol is an isocoumarin metabolite produced by selected species of Streptomyces. Reticulol was first described as a potent inhibitor of cyclic nucleotide phosphodiesterase but more recent research has demonstrated a topoisomerase I inactivation mechanism. Reticulol also causes dose dependent inhibition of lung metastasis in the B16F10 melanoma model.

Additional Information

Synonyms	6,8-Dihydroxy-7-methoxy-3-methylisocoumarin
Product #	R-2595
CAS #	26246-41-3
Chemical Name	6,8-Dihydroxy-7-methoxy-3-methylisocoumarin
Formula	C₁₁H₁₀O₅
MW	222.2
Appearance	White Powder
Purity	>95% by HPLC
Solubility	Soluble in water, methanol, DMSO, ethanol (moderate), and DMF
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	Antitumor efficacy of reticulol against the lung metastasis model B16F10 melanoma

Additional Information

MDL Number	MFCD11111617
ChemACX	X2982835-5
InChI	InChI=1S/C11H10O5/c1-5-3-6-4-7(12)10(15-2)9(13)8(6)11(14)16-5/h3-4,12-13H,1-2H3
SMILES	Cc1cc2cc(c(c(c2c(=O)o1)O)OC)O

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