Retapamulin

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产品名称: Retapamulin

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简单介绍

CAS:224452-66-8Formula:C30H47NO4SMW:517.8Appearance:WhitesolidPurity:>99%byHPLC

Retapamulin 的详细介绍

*Please inquire the availability for this product. Retapamulin is a semi-synthetic pleuromutilin prepared by reacting pleuromutilin tosylate with tropine-3-thiol to give a more hydrophobic analogue with a tertiary amine. This enables formulation as a stable hydrochloride salt. Retapamulin is a broad spectrum antibiotic with no cross resistance to existing antibiotic classes, and is the first pleuromutilin approved for human use. Like all the pleuromutilins, retapamulin inhibits protein synthesis by binding to domain V of 23S rRNA.

Additional Information

Synonyms	SB 275833
Product #	R-2593
CAS #	224452-66-8
Formula	C30H47NO4S
MW	517.8
Appearance	White solid
Purity	>99% by HPLC
Therapeutic Area	Infectious Diseases
Use	Retapamulin is a broad spectrum antibiotic treating skin infection

Additional Information

MDL Number	MFCD11045316
InChI	InChI=1S/C30H47NO4S/c1-7-28(4)16-24(35-25(33)17-36-22-14-20-8-9-21(15-22)31(20)6)29(5)18(2)10-12-30(19(3)27(28)34)13-11-23(32)26(29)30/h7,18-22,24,26-27,34H,1,8-17H2,2-6H3/t18-,19+,20-,21+,22-,24-,26+,27+,28-,29+,30+/m1/s1
SMILES	C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@@]1([C@@H](C[C@@]([C@H]([C@@H]3C)O)(C)C=C)OC(=O)CS[C@@H]4C[C@H]5CC[C@@H](C4)N5C)C

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