Ratjadone C (native)

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产品名称: Ratjadone C (native)

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简单介绍

Formula:C28H40O5MW:456.6Appearance:LiquidPurity:95%

Ratjadone C (native) 的详细介绍

Cytotoxic secondary metabolite that inhibits cell growth of mammalian cell lines in the picomolar range (IC50=0.2ng/ml with L929 mouse cells) including multi-drug resistant HeLa cells (IC50=0.1ng/ml with KB-V1).

Additional Information

Product #	R-1143
Chemical Name	(2R)-2-[(1E,3Z,5R,7E,9E,11R)-3-ETHYL-11-HYDROXY-11-[(2S,4R,5S,6S)-4-HYDROXY-5-METHYL-6-[(E)-PROP-1-ENYL]TETRAHYDROPYRAN-2-YL]-5-METHYL-UNDECA-1,3,7,9-TETRAENYL]-2,3-DIHYDROPYRAN-6-ONE
Formula	C₂₈H₄₀O₅
MW	456.6
Appearance	Liquid
Purity	95%
Solubility	Soluble in methanol (50mg/ml). Sparingly soluble in aqueous buffers (up to 10g/ml in PBS).
Melting Point	-98 °C
Preparation	Acid and base sensitive. Unstable in acidic and alkaline buffer systems (pH <6 or>7). Stable in methanolic solution at -20°C.
Storage Temp	-20°C

Additional Information

MDL Number	MFCD08062315
InChI	InChI=1S/C28H40O5/c1-5-11-26-21(4)25(30)19-27(33-26)24(29)14-9-7-8-12-20(3)18-22(6-2)16-17-23-13-10-15-28(31)32-23/h5,7-11,14-18,20-21,23-27,29-30H,6,12-13,19H2,1-4H3/b8-7+,11-5+,14-9+,17-16+,22-18-/t20-,21+,23-,24-,25-,26+,27+/m1/s1
SMILES	C/C=C/[C@H]1[C@H]([C@@H](C[C@H](O1)[C@@H](/C=C/C=C(C)/C[C@@H](C)/C=C(/C)C=C[ C@H]2CC=CC(=O)O2)O)O)C

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