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AGScientific
QS11
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产品名称:
QS11
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简单介绍
CAS:944328-88-5Formula:C36H33N5O2MW:567.68Appearance:WhiteSolidPurity:98%byHPLC
QS11
的详细介绍
Inhibits the GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) as well as synergizes the Wnt/-catenin signaling pathway. The Wnt/-catenin signaling pathway regulates cell fate and behavior during embryogenesis, ***** tissue homeostasis, and regeneration.
Additional Information
Synonyms
(2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol
Product #
Q-2411
CAS #
944328-88-5
Chemical Name
(2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol
Formula
C
36
H
33
N
5
O
2
MW
567.68
Appearance
White Solid
Purity
98% by HPLC
Solubility
Soluble in DMSO (10 mg/ml)
Storage Temp
+4°C
Therapeutic Area
Oncological Disorders
Use
QS11 inhibits migration of ARFGAP overexpressing breast cancer cells
Additional Information
MDL Number
MFCD18086864
ChemACX
X2273893-4
InChI
InChI=1S/C36H33N5O2/c42-23-31(20-25-8-3-1-4-9-25)38-34-33-35(40-36(39-34)43-32-19-18-28-12-7-13-30(28)21-32)41(24-37-33)22-26-14-16-29(17-15-26)27-10-5-2-6-11-27/h1-6,8-11,14-19,21,24,31,42H,7,12-13,20,22-23H2,(H,38,39,40)/t31-/m0/s1
SMILES
c1ccc(cc1)C[C@@H](CO)Nc2c3c(nc(n2)Oc4ccc5c(c4)CCC5)n(cn3)Cc6ccc(cc6)c7ccccc7
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