Pyridomycin

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产品名称: Pyridomycin

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简单介绍

CAS:18791-21-4Formula:C27H32N4O8MW:540.6Appearance:PinkresiduePurity:>95%byHPLC

Pyridomycin 的详细介绍

*Please inquire the availability for this product. Pyridomycin is a potent antibiotic active against mycobacteria and some Gram negative bacteria, originally isolated from Streptomyces abidoflavus by Umezawa group at the NIH Japan in 1953, and since isolated from different species and published under several names. The unusual 12-membered macrocyclic depsipeptide comprises three unique sub-units incorporating two substituted pyridines. Pyridomycin is thought to target NADH-dependent enoyl (acyl-carrier-protein) reductase InhA. Recent reports of activity against isoniazid-resistant mycobacteria has seen pyridomycin identified as a potential lead for new generation antibiotics.

Additional Information

Synonyms	U24544, Antibiotic U24544, Erizomycin
Product #	P-2803
CAS #	18791-21-4
Formula	C27H32N4O8
MW	540.6
Appearance	Pink residue
Purity	>95% by HPLC
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	Pyridomycin is a potent antibiotic active against mycobacteria and some Gram negative bacteria

Additional Information

InChI	InChI=1S/C27H32N4O8/c1-5-14(2)23-27(37)38-16(4)20(31-25(35)21-19(32)9-7-11-29-21)24(34)30-18(12-17-8-6-10-28-13-17)22(33)15(3)26(36)39-23/h6-11,13,15-16,18,20,22,32-33H,5,12H2,1-4H3,(H,30,34)(H,31,35)/b23-14-/t15-,16-,18+,20+,22+/m1/s1
SMILES	CC/C(=C\1/C(=O)O[C@@H]([C@@H](C(=O)N[C@H]([C@H]([C@H](C(=O)O1)C)O)Cc2cccnc2)NC(=O)c3c(cccn3)O)C)/C

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