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Pseudomonic acid, Pseudomonas

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产品名称: Pseudomonic acid, Pseudomonas
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简单介绍

CAS:12650-69-0Formula:C26H44O9MW:500.6Appearance:Whitesolid.Purity:>95%byHPLC


Pseudomonic acid, Pseudomonas  的详细介绍

Pseudomonic acid is a potent antibiotic produced by Pseudomonas fluorescens reported by Fuller et al. in 1971.
Pseudomonic acid has broad spectrum activity against Gram positive bacteria and was approved for topical human use in 1985. Pseudomonic acid acts asa potent and selective inhibitor of isoleucyl-tRNA synthetase.

Additional Information

SynonymsMupirocin, Bactroban, Eismycin, Antibiotic BRL 4910A, Antibiotic Y 11633
Product #P-1639
CAS #12650-69-0
FormulaC26H44O9
MW500.6
AppearanceWhite solid.
Purity>95% by HPLC
SolubilitySoluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Melting Point75-78 °C
Storage Temp-20°C
Therapeutic AreaInfectious Diseases
UseMupirocin is used as a topical treatment for bacterial skin infections

Additional Information

MDL NumberMFCD01711620
InChIInChI=1S/C26H44O9/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29)/b16-13+/t17-,18-,19-,20-,21-,24+,25-,26-/m0/s1
SMILESC[C@H]([C@H]1[C@@H](O1)C[C@H]2CO[C@H]([C@@H]([C@@H]2O)O)C/C(=C/C(=O)OCCCCCCCCC(=O)O)/C)[C@H](C)O
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