Pravastatin sodium

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产品名称: Pravastatin sodium

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简单介绍

CAS:81131-70-6Formula:C23H35O7NaMW:446.5Appearance:WhitepowderPurity:>98%byHPLC

Pravastatin sodium 的详细介绍

*Please inquire the availability for this product. Pravastatin sodium is the salt of pravastatin, a ring-opened member of the statin family. Pravastatin is produced biosynthetically from compactin (mevastatin) by a number of microorganisms, notably Absidia, Cunninghamella, Syncephalastrum, Nocardia or Streptomyces. Typically, statins like compactin, lovastatin and simvastatin possess a β-hydroxy lactone ring which is a pro-drug for the readily ring-opened dihydroxyacid generally regarded as the active HMG-CoA reductase inhibitor. Importantly, the free carboxylic acid enables pravastatin to be freely water soluble within biological pH ranges.

Additional Information

Synonyms	Mevalotin, CS 514, SQ 3100
Product #	P-2787
CAS #	81131-70-6
Formula	C₂₃H₃₅O₇Na
MW	446.5
Appearance	White powder
Purity	>98% by HPLC
Solubility	Soluble in water
Melting Point	171.2-173 °C
Storage Temp	4°C
Therapeutic Area	Metabolic Disorders
Use	Pravastatin Sodium is a competitive HMGCR (HMG-CoA reductase) inhibitor that potently blocks cholesterol synthesis

Additional Information

MDL Number	MFCD00887601
InChI	InChI=1S/C23H36O7.Na/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28;/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28);/q;+1/p-1/t13-,14-,16+,17+,18+,19-,20-,22-;/m0./s1
SMILES	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)[O-])O)O)O.[Na+]

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