PPAR-gamma Antagonist, G3335

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产品名称: PPAR-gamma Antagonist, G3335

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简单介绍

CAS:36099-95-3Formula:C16H19N3O5MW:333.34Appearance:WhiteSolidPurity:97%byelementalanalysis

PPAR-gamma Antagonist, G3335 的详细介绍

Cell-permeable. A dipeptide that acts as a selective and reversible PPARg antagonist (KD ~ 8 M). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC= 31.9 M) in transfected COS-7 cells.

Additional Information

Synonyms	G3335; H-Trp-Glu-OH
Product #	P-2406
CAS #	36099-95-3
Chemical Name	2-[[2-AMINO-3-(1H-INDOL-3-YL)PROPANOYL]AMINO]PENTANEDIOIC ACID
Formula	C₁₆H₁₉N₃O₅
MW	333.34
Appearance	White Solid
Purity	97% by elemental analysis
Solubility	Soluble in Water
Storage Temp	-20°C
Therapeutic Area	Endocrinological Disorders
Use	A cell-permeable dipeptide that acts as a selective PPAR-γ antagonist used in diabetes

Additional Information

MDL Number	MFCD00037964
ChemACX	X1096243-7
InChI	InChI=1S/C16H19N3O5/c17-11(7-9-8-18-12-4-2-1-3-10(9)12)15(22)19-13(16(23)24)5-6-14(20)21/h1-4,8,11,13,18H,5-7,17H2,(H,19,22)(H,20,21)(H,23,24)/t11-,13-/m0/s1
SMILES	C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)N

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