Pleuromutilin

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产品名称: Pleuromutilin

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简单介绍

CAS:125-65-5Formula:C22H34O5MW:378.5Appearance:WhitesolidPurity:>95%byHPLC

Pleuromutilin 的详细介绍

*Please inquire the availability for this product. Pleuromutilin is a diterpene produced by several species of basidomycete, notably the genus Pleurotus, discovered in 1951. Pleuromutilin is a potent and highly selective antibiotic active against a range of Gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action. Pleuromutilin inhibits protein synthesis by binding to domain V of 23S rRNA and this has led to the development of many semi-synthetic analogues as new generation antibiotics, such as tiamulin and retapamulin.

Additional Information

Synonyms	Drosophilin B, A 40104C
Product #	P-2783
CAS #	125-65-5
Formula	C₂₂H₃₄O₅
MW	378.5
Appearance	White solid
Purity	>95% by HPLC
Solubility	Soluble in ethanol, methanol, DMF and DMSO Limited water solubility
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	Pleuromutilin is a potent and highly selective antibiotic active against a range of Gram positive bacteria

Additional Information

MDL Number	MFCD28154633
InChI	InChI=1S/C22H34O5/c1-6-20(4)11-16(27-17(25)12-23)21(5)13(2)7-9-22(14(3)19(20)26)10-8-15(24)18(21)22/h6,13-14,16,18-19,23,26H,1,7-12H2,2-5H3/t13-,14+,16-,18+,19+,20-,21+,22+/m1/s1
SMILES	C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@@]1([C@@H](C[C@@]([C@H]([C@@H]3C)O)(C)C=C)OC(=O)CO)C

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