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PJ-34

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产品名称: PJ-34
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简单介绍

CAS:344458-15-7Formula:C17H17N3O2.HCIMW:316.786Appearance:SolidPowderPurity:98%


PJ-34  的详细介绍
Potent, water-soluble poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor.

Additional Information

SynonymsN-(6-oxo-5,6-dihydrophenanthridin-2-yl)-N, N-dimethylacetamide.HCl
Product #P-1455
CAS #344458-15-7
Chemical NameN-(6-oxo-5,6-dihydrophenanthridin-2-yl)-N, N-dimethylacetamide.HCl
FormulaC17H17N3O2.HCI
MW316.786
AppearanceSolid Powder
Purity98%
SolubilitySoluble in water (22 mg/ml), and DMSO
Storage Temp+4°C
Therapeutic AreaOncological Disorders
UsePJ34, an inhibitor of PARP-1, suppresses cell growth and enhances the suppressive effects of cisplatin in liver cancer 

Additional Information

MDL NumberMFCD03452993
ChemACXX1343324-6
InChIInChI=1S/C17H16N2O2.ClH/c1-19(2)16(20)10-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(21)18-15;/h3-9H,10H2,1-2H3,(H,18,21);1H
SMILESCN(C)C(=O)Cc1ccc2c(c1)c3ccccc3c(=O)[nH]2.Cl
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