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Pimozide

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产品名称: Pimozide
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简单介绍

CAS:2062-78-4Formula:C28H29F2N3OMW:461.55Appearance:WhiteSolidPurity:98%byTLC


Pimozide  的详细介绍
Cell-permeable. An antipsychotic drug and D2 dopamine receptor antagonist; binds with high affinity to the cloned 5-HT7 receptor. A Stat5 inhibitor; decreases Stat5 tyrosine phosphorylation, but does not affect Bcr-Abl or other tyrosine kinases.

Additional Information

Synonyms1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
Product #P-2397
CAS #2062-78-4
Chemical Name1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
FormulaC28H29F2N3O
MW461.55
AppearanceWhite Solid
Purity98% by TLC
SolubilityDMSO (100 mM)
Melting Point214-218 °C
Storage Temp2-8°C
Therapeutic AreaPsychological Disorders
UsePimozide is a D2DR inhibitor and antipsychotic which binds with very high affinity and inhibits SR-7

Additional Information

MDL NumberMFCD00055081
ChemACXX1004358-8
InChIInChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)
SMILESc1ccc2c(c1)[nH]c(=O)n2C3CCN(CC3)CCCC(c4ccc(cc4)F)c5ccc(cc5)F
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