Pimecrolimus

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产品名称: Pimecrolimus

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简单介绍

CAS:137071-32-0Formula:C43H68ClNO11MW:810.45Appearance:WhitesolidPurity:≥98%

Pimecrolimus 的详细介绍

Pimecrolimus is a cell-selective inhibitor of inflammatory cytokines developed for the treatment of inflammatory skin diseases, such as allergic contact dermatitis, atopic dermatitis, plaque-type psoriasis, and irritant contact dermatitis. It reduces the production of inflammatory cytokines in T cells and mast cells and inhibits the release of preformed inflammatory mediators from mast cells.

Additional Information

Product #	P-2396
CAS #	137071-32-0
Chemical Name	Elidel, SDZ-ASM-982
Formula	C₄₃H₆₈ClNO₁₁
MW	810.45
Appearance	White solid
Purity	≥98%
Solubility	DMSO (25 mg/ml) or EtOH (25 mg/ml)
Storage Temp	-20°C
Therapeutic Area	Dermatological Disorders
Use	Pimecrolimus is an immunomodulating agent used in the treatment of atopic dermatitis

Additional Information

MDL Number	MFCD00901792
InChI	InChI=1S/C43H68ClNO11/c1-10-30-18-24(2)17-25(3)19-36(53-8)39-37(54-9)21-27(5)43(51,56-39)40(48)41(49)45-16-12-11-13-32(45)42(50)55-38(28(6)33(46)23-34(30)47)26(4)20-29-14-15-31(44)35(22-29)52-7/h18,20,25,27-33,35-39,46,51H,10-17,19,21-23H2,1-9H3/b24-18+,26-20+/t25-,27+,28+,29-,30+,31-,32-,33-,35+,36-,37-,38+,39+,43+/m0/s1
SMILES	CC[C@@H]1/C=C(/C[C@@H](C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC1=O)O)C)/C(=C/[C@@H]4CC[C@@H]([C@@H](C4)OC)Cl)/C)O)C)OC)OC)C)\C

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